Flaxseed oil- if you are already familiar with it, you may relate to many of its uses.If you don’t know the slightest about it, you will thank me at the end of the article.
Flaxseed oil, which is also commonly known as linseed oil, is often colourless or a pale yellow coloured fluid, from ripe flax seeds gone through the drying process.
The Scientific name of the plant from which it can be obtained is Linum usitatissimum.
‘What are some of its general applications?’, you may ask!
It is a type of drying oil, meaning it can polymerize to a solid form. Due to such properties of the oil, it can be used for impregnating resins or solvents, by combination or just direct application.
It is used in the production of various materials such as linoleum, pigment binder for oil paints, hardener and plasticiser in putty, and varnish in wood polishing.
It is also edible oil in demands for a nutritional supplement, being the source of α-Linolenic acid (an omega-3 fatty acid).
In many parts of Europe, it is traditionally had with potatoes and quark. It may be classified as a delicacy (yum yum!) due to its hearty taste, which enhances the flavour of quark, which would otherwise be bland.
- Uses Of Flax Seed Oil
- Nutritional supplement and food
- CHEMICAL ASPECTS
- Health Benefits Of Flaxseed Oil
- 1. USE AS A VITAMIN/SUPPLEMENT
- 2. SUGGESTED TREATMENT USES
- 3. Attention deficit-hyperactivity disorder (ADHD)
- 4. (Atherosclerosis)”Hardening of the arteries”
- 5. Breast cancer
- 6. Heart disease
- 7. Dry eyes
- 8. Dry skin
- 9. Exercise performance
- 10. HIV
- 11. High blood pressure
- 12. An ovary disorder is known as polycystic ovary syndrome(PCOS)
- 13. Prostate cancer
- Flaxseed oil is possibly ineffective for the following:
- Side Effects Of Flax seed Oil
- SPECIAL PRECAUTIONS & WARNINGS
- REASONS WHY FLAXSEED SHOULD NEVER BE NEGLECTED
- THE VERDICT
Uses Of Flax Seed Oil
Almost everything has multiple uses, right?
Well! True indeed! But it is always a good idea to know the exact uses if you want to benefit from it truly.
Most of the applications make use of its drying properties, i.e., the starting material is liquid or, at least, pliable, and the older material is rigid but not brittle.
The water-repelling (hydrophobic) property of the resulting hydrocarbon-based material is a plus point.
i. Paint binder
It is a common carrier used for oil paint. It is also used as a painting medium because it makes oil paints more fluid, glossy and enhances transparency.
Also, available in various forms as cold-pressed, alkali-refined, sun-bleached, sun-thickened, and polymerised. The discovery of linseed oil proved a significance advance in the advancement of oil painting.
Traditional glazing putty, made of chalk powder paste and linseed oil, is a sealant for glass windows that hardens within a few weeks of applying and can be painted over later. This utility, as a putty can be owed to the drying properties.
iii. Wood finish
When used for wood finishing, it dries gradually and shrinks by some amount upon hardening. It does not cover the surface as varnish would, but soaks into (visible and non-visible) pores, leaving shiny but not a glossy surface that shows off the grain of the wood.
This finish can be easily repaired, but it provides no significant protection against scratching. The finishes with only wax are less protective. Liquid water can penetrate a linseed oil finish in a few minutes, and water vapour can bypass it almost completely.
Garden furniture finished with linseed oil may have chances of developing mildew. Oiled wood has chances of being yellowish and will likely darken with age. Because it fills the pores, it partially protects wood from being dented by compression.
Boiled linseed oil can be used as sizing traditional oil gilding to attach sheets of a gold leaf to any substrate (canvas, parchment, Armenian bole, etc.).
It has quite a longer working time than the water-based size and gives a steady, smooth surface which is adhesive enough for at least first half of a day after application to cause the gold to stick or stay attached to the surface intended.
It is used to bind wood dust, cork particles, and such materials in the manufacture of floor covering linoleum.Linoleum was an ideal form of home and industrial floor covering starting the 1870s until late 1970s after which it was majorly replaced by PVC(‘vinyl’) floor coverings.
However, from the 1990s, linoleum is once again on the rise, being more environmentally sound than PVC. Linoleum has also given its name to the printmaking technique linocut, wherein a relief design has to be cut into a smooth surface and then inked; subsequently used to print an image. The achieved results are quite similar to those obtained by woodcut
Nutritional supplement and food
Flax seed oil is easily oxidised, and becomes rancid rapidly, with an unpleasant odour, unless it is refrigerated.
Even if kept under cool conditions, it shows a shelf-life of only a few It is not recommended for cooking use, yet a study does show that alpha-linolenic acid (ALA)while bound in flaxseed, was found to be usable for the kitchen.
When bound to flaxseed, the ALA can withstand temperatures up to 350F (176.67C) for 2 hours.
Food-grade flaxseed oil is cold-pressed, obtained without any solvent extraction, in oxygen absence, and marketed as edible oil. Fresh, unprocessed and refrigerated, linseed oil can be used as a nutritional supplement and is also a traditional European ethnic food, regarded especially for its hearty taste.
It contains one of the highest levels of the omega-3 fatty acid ALA among all vegetable oils.Regular linseed oil contains between 52% and 63% ALA (C18:3 n-3). But plant breeders have developed flaxseed with both higher ALA (70%) and lowest ALA content (< 3%).
- Animal care products
- Bicycle maintenance
- Composition ornaments for moulded decoration
- Earthen floors
- Animal feeds
- Industrial lubricant
- Leathers treatment
Having looked at the uses, it makes us wonder, ‘WHAT makes flaxseed oil a part of so many products?’. This is where it’s real information; the chemical composition comes handy.
Flaxseed oil is a triglyceride, like all other fats. It is distinctive for it’s not so usually a large amount of α-linolenic acid, which has a very distinctive reaction with oxygen contained in air. Specifically, the fatty acids contained in linseed oil are of the following types:
- Triply unsaturated α-linolenic acid (51.9-55.2%),
- Saturated acids palmitic acid(at 7%) and stearic acid (at 3.4-4.6%),
- Monounsaturated oleic acid(18.5-22.6%),
- Doubly unsaturated linoleic acid(at 14.2-17%).
Having high contents of desaturated and tri-unsaturated esters, it is particularly susceptible to polymerization reactions when exposed to oxygen in the air. This polymerization, also known as drying, results in rigidification of the material.
This process can be so exothermic that it poses a fire hazard under certain conditions. To prevent it from drying prematurely, linseed oil-based products (oil paints, putty) are required to be stored in air-tight containments.
Like other drying oils, linseed oil exhibits fluorescence under Ultraviolet light once degraded.
Health Benefits Of Flaxseed Oil
1. USE AS A VITAMIN/SUPPLEMENT
When I said Flaxseed OIL, the first thing that may have come into the mind would have been, ‘Is it edible?’Of course, it is! And following are some of its many uses as a food supplement.
Flaxseed oil can be used for many different conditions, like rheumatoid arthritis and high cholesterol.
It is also applicable for treating anxiety, osteoarthritis, benign prostatic hyperplasia (BPH), drying of eyes, vaginal infections, “hardening of arteries” (atherosclerosis), high blood pressure, heart diseases, diabetes and an attention disorder (ADHD).
Many people also use it as a laxative for constipation, for losing weight, and to prevent breast and prostate cancer.
It can also be applied to the skin for soothing irritations or soften its roughness.In foods, it ca be used as cooking oil and mainly in margarine.
2. SUGGESTED TREATMENT USES
Not only is it a food supplement for a few diseases, but it also helps in the treatment of some very common diseases. Some of the uses are given below are surely going to benefit you!
There is insufficient evidence for the following uses:
3. Attention deficit-hyperactivity disorder (ADHD)
There is some evidence that taking flaxseed oil may improve attention, restlessness, impulsiveness, and self-control in children with ADHD.
There are some other essential oils for ADHD that help to treat this.
4. (Atherosclerosis)”Hardening of the arteries”
Changing the amount of linolenic acid in the diet can help in preventing hardening of the arteries. Flaxseed oil has parts of linolenic acid, and thereby some people suggest that it might help to prevent atherosclerosis. Though this assumption looks quite reasonable, there has been no research yet to prove its correctness.
5. Breast cancer
Women who have higher levels of alpha-linolenic acid in their breast tissue are likely to get breast cancer very less. Scientists think that higher intakes of linoleic acid may protect against breast cancer.
Flaxseed oil is the primary source of linolenic acid. However, it is not proven whether increasing flaxseed oil intake would help to prevent breast cancer or not.
6. Heart disease
People with an existing heart disease consuming more alpha-linolenic acid in their food plan seem to have lowered the risk of dying from heart disease. It is one source of alpha-linolenic acid.
However, researchers have not directly measured any effect of flaxseed oil intake on heart disease outcomes. It is also unknown if flaxseed oil supplements have the same effects as flaxseed oil intake from food.
Almond Oil also prevents heart ailments and regulates blood pressure.
7. Dry eyes
Early research suggests that taking flaxseed oil reduces irritation and symptoms of dry eyes. A product containing fish oil plus flaxseed oil (TheraTears Nutrition) can also reduce symptoms of dry eye and increase tear production.
Eye problems and dry eyes can be treated with the use of Black Currant Essential Oil.
8. Dry skin
There is inconsistent evidence regarding effects of flaxseed oil for dry skin. Some researchers suggest that taking flaxseed oil by medium from the mouth with alpha-tocopherol daily for 12 weeks did not improve skin moisture in women with dry skin.
However, others suggest that taking flaxseed oil in a similar for the same length of time can improve moisture and roughness of the skin.
9. Exercise performance
Low-quality research has suggested that α-linolenic acid, a chemical in flaxseed oil, will not improve muscle strength in older adults.
Early research suggests taking a formula with contents arginine, RNA, yeast and alpha-linolenic acid, improves weight gain, but not immunity function in people with HIV.
11. High blood pressure
Studies suggest that flaxseed oil supplements help in lowering blood pressure in men with normal blood pressure and high cholesterol. It is not clear if it will lower blood pressure in people with high blood pressure or not.
12. An ovary disorder is known as polycystic ovary syndrome(PCOS)
Research suggests that taking flaxseed oil for six weeks may help in lowering triglyceride levels, but would not affect weight, blood sugar, or cholesterol levels in the women diagnosed with PCOS.
Consuming alpha-linolenic acid in diet seems to be linked to reducing a risk of developing pneumonia.
However, research has not directly measured any effect of flaxseed oil intake on outcomes of pneumonia. It is also unknown if flaxseed oil supplements will have the same effects as flaxseed oil contained from food.
You can also follow some other home remedies to treat PCOS.
13. Prostate cancer
Research is inconsistent on effects of the flaxseed oil ingredient, α-linolenic acid, in prostate cancer. Some research suggests that high intake of alpha-linolenic acid is linked with an increase in the risk of prostate cancer.
Others suggest high intake or high blood levels of alpha-linolenic acid is not linked overall with any risk of prostate cancer; however, extra amounts of alpha-linolenic acid might worsen existing prostate cancer.
The source of alpha-linolenic acid is important. Alpha-linolenic acid from dairy and meat sources can be positively linked with prostate cancer; however the acid from plant sources, such as flaxseed or flaxseed oil, should not affect prostate cancer risk.
- Weight loss
- Vaginal issues
- Other conditions
Yes! Yes! It seems that flaxseed oil is a medical boon, it helps in almost every condition. But also note that there are a few restrictions.
Flaxseed oil is possibly ineffective for the following:
Researchers suggest that taking flaxseed oil on a daily basis for 16 weeks does not improve symptoms of mania or depression in children having bipolar disorder.Also, it does not lower blood sugar or improves insulin levels in people with diabetes of type 2.
2. High cholesterol
Early research suggests that taking flaxseed oil daily for a time of 3 months lowers total cholesterol in people with high cholesterol.
This early research, however, can not be said reliable. More high-quality proof suggests that flaxseed oil does not help reduce cholesterol levels in people with previously high cholesterol and high triglycerides.
3. Rheumatoid arthritis (RA)
Taking flaxseed oil daily for three months seems not to improve the effects of pain and stiffness, and has no effect on laboratory tests that measure the severity of RA.
Side Effects Of Flax seed Oil
It looks like flaxseed oil is a must-include in a daily diet, due to its disease-helping information. But also, one thing to always take care is, you don’t exceed using it.
It might be an ultimate food supplement, but it also has a few side- effects, which you probably don’t want to get into trouble with!
Flaxseed oil is LIKELY SAFE for most adults when taken orally in appropriate amounts.However, large doses of 30 grammes/day or higher can cause loose stools and diarrhoea.
Also, note that allergic reactions have been recorded to have occurred while taking flaxseed oil.
Some men worry taking flaxseed oil because it might increase the chance of getting prostate cancer due to the α-linolenic acid that is contained in it.
Researchers are still trying to find out the role of the alpha-linolenic acid in prostate cancer. Some researchers suggest that alpha-linolenic acid may increase the risk of getting or make existing prostate cancer worse, but other studies have found no such connection.
Nevertheless, the α-linolenic acid in flaxseed oil does not seem to be any problem. Alpha-linolenic acid obtained from natural sources like plants, such as flaxseed, does not seem to affect the risk of prostate cancer, although alpha-linolenic acid obtained from dairy and meat sources has been linked in few studies with prostate cancer.
Enough is not known about the safety of flaxseed oil when applied to the skin.
So take care, before blindly trusting flaxseed oil for only its advantages.
SPECIAL PRECAUTIONS & WARNINGS
Please do go through following precautions, to be on the safe-side and using flaxseed oil wisely; because the wiser you are maximum you will benefit!
Flaxseed oil is POSSIBLY UNSAFE when taken orally during pregnancy. Some researchers suggest that flaxseed oil may increase the chance of premature birth if taken during the second or third trimesters of the pregnancy.
However, others suggest that taking flaxseed oil might be safe if starting from second or third trimester and continued until delivery. Until anymore is known, pregnant women should avoid taking flaxseed oil.
Flaxseed is POSSIBLY SAFE for children when taken orally, for short-term.
There isn’t reliable enough information available about the safety of flaxseed oil during breastfeeding. Avoiding using it while breastfeeding will be safe until more is known.
Flaxseed oil may increase the risk of severe bleeding in patients having bleeding disorders. It is best to talk to your healthcare professional before using flaxseed oil if you have a bleeding disorder.
Flaxseed oil may increase the risk of bleeding during and after any surgery. It is required to stop using it at least 2 weeks beforehand scheduled surgery.
Given advantages and precautions, the question arising in curious minds will be, ‘How much will be too much?’ Or ‘How much should I take so that I end up only in advantage’. This will surely answer any such questions.
The appropriate dose of flaxseed oil depends on various factors such as user’s age, health, and other conditions. Currently, there is not much scientific information to determine proper range of prescribed doses for flaxseed oil.
It should be kept in mind that natural products are not necessarily safe and dosages are important. Always be sure to follow given directions on product labels and consult a pharmacist or physician or any other health professional before using.
Note that the flaxseed oil will easily break down chemically if given exposure to light, heat, or air. It should be stored in a frosted bottle and guarded against heat. It can be ideally stored in the refrigerator.
REASONS WHY FLAXSEED SHOULD NEVER BE NEGLECTED
Going through almost all uses and precautions, one might wonder, ‘What if I don’t use it at all?’.
Well, let me tell you, my friend, ignorance is never good. So before plainly neglecting the idea of including or excluding flaxseed oil in your diet, it is best you know what you may miss while doing so!
According to Center for Disease Control and Prevention, estimated one in three Americans (68 million) has a high blood pressure condition, which is commonly known as hypertension.
The normal blood pressure reading is 120 over 80. (If your blood pressure consistently exceeds these numbers, it is recommended to talk to your doctor.) Fortunately, flaxseed oil is also able to help, as researched byGreek researchers.
In a 12-week study of 59 middle-aged men, the Greek researchers discovered that flaxseed oil consumption results in significantly lowering blood pressure.
Consider adding flaxseed oil to your regular diet and you may help in saving yourself, literally from headaches and other symptoms or causes associated with hypertension.
2. Skin Cancer
Research has already proven how damaging regular tanning can be to your skin. But if you are a sun worshipper, it may be considered smart to consume flaxseed (on top of regular sunscreen).
Omaha researchers found that mice that were fed flaxseed supplements were successful in reducing melanoma tumours by 63%.
The truth of life: Depression hurts. Plenty of antidepressants are available that doctors prescribe; but according to toJapanese studies, simply adding flaxseed to your diet proved much useful.
The study found that patients are having significant depression levels also suffered from low levels of docosahexaenoic and eicosapentaenoic acids – exact acids that are found in a variety of foods such as fish, walnuts, and flax. Eat up, as theory suggests, and it may help correct those imbalances.
If you are living healthy and fit lifestyle, but still can’t shake your consumption of alcohol?
Just like any other self-destructive behaviours, you might be putting yourself at a big risk. One very serious possibility can be liver disease.
Fortunately, those who cannot seem to help themselves, there are ways to decrease risks involved with the liverRecent researchers of 30 men found that, who received flaxseed lignan capsules, could effectively reduce the liver disease risk factors.
It was concluded that 100 mg supplementation can be beneficial. (Of course, the best idea would be to stop drinking.)
It all finally comes down to just one decision: to have or not to have flaxseed oil regularly?
Natural flaxseed oil is packed with numerous health benefits that you can’t probably go wrong with.
A daily intake of such healthy oil offers a lot of advantages and goodness. But it is still recommended to talk to a natural health specialist before making organic flaxseed oil a part of your daily routine.
Boelsma E, Hendriks HF. Roza L. Nutritional skin care: health effects of micronutrients and fatty acids. Am J Clin Nutr. 2001;73(5):853-864.
Bommareddy A, Arasada BL, Mathees DP, Dwivedi C. Chemopreventive effects of dietary flaxseed on colon tumor development. Nutr Cancer. 2006;54(2):216-22.
Bruinsma KA, Taren DL. Dieting, essential fatty acid intake, and depression. Nutrition Rev. 2000;58(4):98-108.
Caligiuri SP, Aukema HM, Ravandi A, Guzman R, Dibrov E, Pierce GN. Flaxseed consumption reduces blood pressure in patients with hypertension by altering circulating oxylipins via an a-linolenic acid-induced inhibition of soluble epoxide hydrolase.Hypertension. 2014;64(1):53-9.
Caron MF, White CM. Evaluation of the antihyperlipidemic properties of dietary supplements. Pharmacotherapy. 2001;21(4):481-487.
Cellini M, Caramazzu N, Mangiafico P, Possati GL, Caramazza R. Fatty acid use in glaucomatous optic neuropathy treatment. Acta Ophthalmol Scand Suppl. 1998;227:41-42.
Cho E, Hung S, Willet WC, Spiegelman D, Rimm EB, Seddon JM, et al. Prospective study of dietary fat and the risk of age-related macular degeneration. Am J Clin Nutr. 2001;73(2):209-218.
Clark WF, Kortas C, Heidenheim AP, Garland J, Spanner E, Parbtani A. Flaxseed in lupus nephritis: a two–year nonplacebo-controlled crossover study. J Am Coll Nutr. 2001;20(2 Suppl):143-148.
Curtis CL, Hughes CE, Flannery CR, Little CB, Harwood JL, Caterson B. N-3 fatty acids specifically modulate catabolic factors involved in articular cartilage degradation. J Biol Chem. 2000;275(2):721-724.
Dahl WJ, Lockert EA, Cammer AL, Whiting SJ. Effects of flax fiber on laxation and glycemic response in healthy volunteers. J Med Food. 2005;8(4):508-11.
de Logeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation. 1999;99(6):779-785.
Demark-Wahnefried W, Price DT, Polascik TJ, et al. Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features. Urology. 2001;58(1):47-52.
Deutch B. Menstrual pain in Danish women correlated with low n-3 polyunsaturated fatty acid intake. Eur J Clin Nutr. 1995;49(7):508-516.
Dew TP, Williamson G. Controlled flax interventions for the improvement of menopausal symptoms and postmenopausal bone health: a systematic review. Menopause. 2013;20(11):1207-15.
Dodin S et al. Flaxseed on cardiovascular disease markers in healthy menopausal women: a randomized, double-blind, placebo-controlled trial. Nutrition. 2008;24(1):23-30.
Dodin S, Lemay A, Jacques H, Legare F, Forest JC, Masse B. The effects of flaxseed dietary supplement on lipid profile, bone mineral density, and symptoms in menopausal women: a randomized, double-blind, wheat germ placebo-controlled clinical trial. J Clin Endocrinol Metab. 2005;90(3):1390-7.
Edwards R, Peet M, Shay J, Horrobin D. Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. J Affect Disord. 1998;48(2-3):149-155.
Freeman VL, Meydani M, Yong S, Pyle J, Flanigan RC, Waters WB, Wojcik EM. Prostatic levels of fatty acids and the histopathology of localized prostate cancer. J Urol. 2000;164(6):2168-2172.
Frieri G, Pimpo MT, Palombieri A, Melideo D, Marcheggiano A, Caprilli R, et al. Polyunsaturated fatty acid dietary supplementation: an adjuvant approach to treatment of Helicobacter pylori infection. Nut Res. 2000;20(7):907-916.
Geerling BJ, Badart-Smook A, van Deursen C, van Houwelingen AC, Russel MG, Stockbrugger RW, et al. Nutritional supplementation with N-3 fatty acids and antioxidants in patients iwth Crohn’s disease in remission: effects on antioxidant status and fatty acid profile. IBD. 2000;6(2):77-84.
GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial.Lancet. 1999;354:447-455.
Griel AE, Kris-Etherton PM, Hilpert KF, Zhao G, West SG, Corwin RL. An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans. Nutr J. 2007;6(1):2 [Epub ahead of print].
Hall C 3rd, Tulbek MC, Xu Y. Flaxseed. Adv Food Nutr Res. 2006;51:1-97.
Hallund J, Tetens I, Bugel S, Tholstrup T, Ferrari M, Teerlink T, Kjaer A, Wiinberg N. Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women. J Nutr. 2006;136(9):2314-8.
Haggans CJ, Hutchins AM, Olson BA, Thomas W, Martini MC, Slavin JL. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Nutr Canc. 1999;33(2):188-195.
Harper CR, Edwards MJ, DeFilipis AP, Jacobson TA. Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans. J Nutr. 2006;136(1):83-7.
Harris WS. N-3 fatty acids and serum lipoproteins: human studies. Am J Clin Nutr. 1997;65(5):1645S (10).
Hibbeln JR, Salem N, Jr. Dietary polyunsaturated fatty acids and depression: when cholesterol does not satisfy. Am J Clin Nut. 1995;62(1):1-9.
Holman RT, Adams CE, Nelson RA, Grater SJ, Jaskiewicz JA, Johnson SB, et al. Patients with anorexia nervosa demonstrate deficiencies of selected essential fatty acids, compensatory changes in nonessential fatty acids and decreased fluidity of plasma lipids. J Nutr. 1995;125:901-907.
Hu FB, Stampfer MJ, Manson JE et al. Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. Am J Clin Nutr. 1999;69:890-897.
Hutchins AM, Martini MC, Olson BA, Thomas W, Slavin JL. Flaxseed consumption influences endogenous hormone concentrations in postmenopausal women. Nutr Cancer. 2001;39(1):58-65.
Jenab M, Thompson LU. The influence of flaxseed and lignans on colon carcinogenesis and ß-glucuronidase activity. Carcinogenesis. 1996;17(6):1343-1348.
Klurfeld DM, Bull AW. Fatty acids and colon cancer in experimental models. Am J Clin Nut. 1997;66(6 Suppl):1530S-1538S.
Kremer JM. N-3 fatty acid supplements in rheumatoid arthritis. Am J Clin Nutr. 2000;(suppl 1):349S-351S.
Kris-Etherton P, Eckel RH, Howard BV, St. Jeor S, Bazzare TL. AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease.Circulation. 2001;103:1823.
Kurzer MS, Xu X. Dietary phytoestrogens. Ann Rev Nutr. 1997;17:353-381.
Laugharne JD, Mellor JE, Peet M. Fatty acids and schizophrenia. Lipids. 1996;31(Suppl):S-163-165.
Leitzmann MF, Stampfer MJ, Michaud DS, Augustsson K, Colditz GC, Willett WC, Giovannucci EL. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer.Am J Clin Nutr. 2004;80(1):204-16.
Lewis JE, Nickell LA, Thompson LU, Szalai JP, Kiss A, Hilditch JR. A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause. Menopause. 2006;13(4):631-42.
Lockwood K, Moesgaard S, Hanioka T, Folkers K. Apparent partial remission of breast cancer in ‘high risk’ patients supplemented with nutritional antioxidants, essential fatty acids, and coenzyme Q10. Mol Aspects Med. 1994;15Suppl:s231-s240.
Lorenz-Meyer H, Bauer P, Nicolay C, Schulz B, Purrmann J, Fleig WE, et al. Omega-3 fatty acids and low carbohydrate diet for maintenance of remission in Crohn’s disease. A randomized controlled multicenter trial. Study Group Members (German Crohn’s Disease Study Group). Scan J Gastroenterol. 1996;31(8):778-785.
Lowcock EC, Cotterchio M, Boucher BA. Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk. Cancer Causes Control. 2013 Apr;24(4):813-6. doi: 10.1007/s10552-013-0155-7. Epub 2013 Jan 25.
Lucas EA, Wild RD, Hammond LJ, Khalil DA, Juma S, Daggy BP, Stoecker BJ, Arjmandi BH. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in postmenopausal women. J Clin Endocrinol Metab. 2002;87(4):1527-32.
Mandasescu S, Mocanu V, Dascalita AM, Haliga R, Nestian I, Stitt PA, Luca V. Flaxseed supplementation in hyperlipidemic patients. Rev Med Chir Soc Med Nat Iasi. 2005;109(3):502-6.
Meydani M. Omega-3 fatty acids alter soluble markers of endothelial function in coronary heart disease patients. Nutr Rev. 2000;58(2 pt 1):56-59.
Moyad M. Soy, disease prevention, and prostate cancer. Sem Urol Oncol. 1999;17(2):97-102.
Mozaffarian D. Does alpha-linolenic acid intake reduce the risk of coronary heart disease? A review of the evidence.Altern Ther Health Med. 2005;11(3):24-30; quiz 31, 79.
Newcomer LM, King IB, Wicklund KG, Stanford JL. The association of fatty acids with prostate cancer risk. Prostate. 2001;47(4):262-268.
Peet M, Laugharne JD, Mellor J, et al. Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. Prostaglandins Leukot Essent Fatty Acids. 1996;55(1-2):71-75.
Prasad K. Flaxseed and cardiovascular health. J Cardiovasc Pharmacol. 2009 Nov;54(5):369-77. Review.
Prasad K. Dietary flaxseed in prevention of hypercholesterolemic atherosclerosis.Atherosclerosis. 1997;132(1):69-76.