Mixing Benadryl and Alcohol can be potent as both of them slows down the CNS(central nervous system).Due to which you might feel drowsiness, sedation and cause trouble doing both mental and physical task.

Benadryl is a brand name of the drug used for treating allergies, hay fever, common cold or a cough. It is an over the counter medication (OTC) used for allergies.

You can get it without any prescription from doctor or pharmacist. Benadryl has antihistamine which blocks the occurring natural histamine in your body.

Histamine is a chemical your immune system produce. It protects your body from foreign particles. It can make you sneeze, tear up, or itch, whatever it takes to get the foreign particle out of your body.

Its overreaction can cause you restlessness and confusion. To suppress the effects of histamine, you need the antihistamine, i.e., Benadryl.

Benadryl is a water-soluble drug and absorbed by the body quickly and reach to the peak level within an hour. It processed by the liver and can remain in the body for approx 24 hours. It can be lethal if used more than 300 milligrams daily. The 300 milligram should also divide into 25-50 milligram doses.

Benadryl For children

Benadryl shouldn’t use for infants below two years. Infants don’t produce histamine in much quantity, and it can affect their brain. Children of 4years or older can take Benadryl but in very less amount. Doses recommend for Children should not be more than 2times in 24 hours.

Uses of Benadryl

  • relieve from allergy
  • hay fever
  • common cold
  • rash,
  • itching,
  • watery eyes,
  • itchy eyes/nose/throat,
  • A cough,
  • A runny nose,

Benadryl is an over the counter treatment for allergies and running nose. You can buy it without any prescription from any local shops. It can make you drowsy and help you to sleep better. There are some common side effects of it.

Common Side Effects Of Benadryl

  • Sedation,
  • tiredness,
  • sleepiness,
  • dizziness,
  • disturbed coordination,
  • constipation,
  • dry mouth/nose/throat,
  • difficulty urinating,
  • Upset stomach.
  • Blurred vision
  • double vision
  • loss of appetite or
  • nausea

What Is Alcohol?

Alcohol is a legal but sedative drug contains no nutrients for the body. It reduces a person’s ability to think rationally and distorts his or her judgment. There are some benefits of alcohol, especially red wine. It is also a depressant which slows down the functioning of the Central Nervous system.

Most of the people drink alcohol to calm themselves. It is found in most of the social gatherings. It has anxiety-reducing property. The human body has a limit for everything. If you drink alcohol more than your body can handle you will experience sedative effects.

It can create the social and physical complication for you. The amount of alcohol drunk determines the type of effect a personal experience.

Drinking alcohol in excess can lead to addiction, cirrhosis of the liver or liver failure. An adult person should not take alcohol more than 75g at a time.

The lethal amount of alcohol for 60 kg person is 300g. It can kill the person. It can stay in your body’s system for 24-48 hours. Also, can be detected by urine, saliva or breath test.

Ethanol Alcohol is only alcohol used in beverages. It produced by fermentation of grains and fruits. It is available in many beverages like beer, wine to the more potent distilled spirits like whiskey.

Side Effect Of Alcohol

  • Lose body’s coordination and control.
  • Inability to feel pain,
  • toxicity where the body vomits the poison
  • unconsciousness worse
  • coma
  • death from severe toxic overdose
  • Potential respiratory depression
  • Urinary incontinence
  • Lethargy
  • Confusion
  • Slower reflexes
  • Decreased heart rate
  • Blurred vision
  • Increase hurt rate.

Benadryl and Alcohol are potent drugs and should be taken with care. Apart from common side effects, taking alcohol with Benadryl can cause severe harm.

Danger of Mixing Benadryl and Alcohol

Danger of Mixing Benadryl and Alcohol

Benadryl and alcohol both are depressant for Central Nervous system of human body. Mixing of both can depress your central Nervous System too much.

1. Sleeping Problem

Benadryl approve as sleeping aid and alcohol also make you drowsy. When Benadryl mixed with alcohol instead of giving you a good sleep it can act as a stimulant. It can make you dizzy and restless.

2. Driving Warning

One of the driving rules is “don’t drink and drive.” When Benadryl added to the alcohol, it enhances the effects of alcohol for a more extended period. A mixture of Benadryl and alcohol can have the greater impact on your ability to stay alert. You can meet with an accident or injuries.

3. Addiction of the combination

Alcohol and Benadryl both are easy to available products at a normal range of price. Many alcoholic find the effect of the combination desirable, but it is harmful to health. The Combination can cause drowsiness and decreased focus. You may find yourself in a life-threatening stage you have no control over.

4. Senior Age Problem

The combination of alcohol and Benadryl can cause much more danger for senior age people. It can be impaired the motor activity of older people and create the cardiac attack in many.

5. Severe Effect Of Alcohol and Benadryl

The tolerability of the combination depends from person to person. Some people may don’t have an effect of the mixture while some develop effect immediately. The combination may have serious consequence on your health.

For the mid effect, you may include nausea and vomiting. The combination may have serious consequence on your health.

For the mid effect, you may include nausea and vomiting. The life-threatening situation can occur if you drink a mixture of alcohol and Benadryl. It can cause internal bleeding and cardiac arrest.

The patients with asthma or COPD are at the high risk of respiratory suppression or failure.


Always avoid having alcohol after Benadryl or vice versa. If you have to drink alcohol wait for few hours until body suppresses the effects of Benadryl.

If you take Benadryl, ask your doctor how long you need to wait before having a glass of alcohol. Never take a combination of alcohol and Benadryl to avoid side effects or consequences.

Some OTC or prescribed medication may contain alcohol up to 10%. Drugs like laxatives and cough syrup have a right amount of alcohol.

These drugs can interact with Benadryl and cause harm to you. To avoid any interaction of alcohol and Benadryl, always read the label before using any medication.

Can Combination of Benadryl and Alcohol kill you?

Yes, it is strong enough to kill you. Excess of any of them is dangerous. Both are Central Nervous system depressant.

The combination gives profound dizziness and drowsiness.The person loses control over the mind and the body.

When combined the depressant effect increase much. It can shut down of Central Nervous system.

What To Do If Someone Had Taken Benadryl and Alcohol Combination?

Effect of Benadryl and alcohol differ from person to person. You can treat the dry mouth caused by Benadryl and alcohol mixture.

Give the patient sugarless hard candy or gum, use ice chips or any juice. Avoid giving any other drugs to the patient.

If a person is feeling sleepy without any problem, let him sleeps. Effect of the combination will suppress by its own.

If vomit or breathing problem occurs, you need to take him to a hospital or consult the doctor immediately.


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